Five millionth Invisalign patient

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Align Technology announces five millionth Invisalign patient and continued commitment to Operation Smile

Align Technology, Inc., the worldwide market leader in clear aligner treatment, has announced that the five millionth patient has started Invisalign treatment. This is recognised as a significant milestone for both the company and the 127,000 Invisalign-trained dentists. It “reflects accelerated adoption of Invisalign treatment globally”.

“It’s very rewarding to see how rapidly Invisalign treatment is growing around the world. I can’t believe our first ‘million’ took ten years to achieve, while our fifth ‘million’ only took one year,” said Joe Hogan, Align Technology president and CEO. “We’re continuing to see a significant increase in adoption of Invisalign treatment globally, especially among teens. In the third quarter of 2017, worldwide Invisalign shipments to teenagers increased 46% compared to the same period last year.

“To date, over one million teenagers have started orthodontic treatment with Invisalign clear aligners. The introduction of Invisalign Teen with Mandibular Advancement gives Invisalign providers even more confidence that they can deliver great outcomes and great treatment experience to teens in their practices.”

Invisalign Teen with mandibular advancement is available from Invisalign providers outside the United States where it is pending 510(k) clearance.

The five millionth patient, a 12 year-old called Hadi, is currently undergoing treatment using Invisalign Teen with mandibular advancement from Invisalign provider Dr. Eugene Kholov. An early adopter of new technology, Dr. Kholov became an Invisalign provider nearly 20 years ago and has since treated over 2,000 Invisalign patients.

He enthused, "With greater comfort and up to 50% shorter treatment times when combined with weekly aligner changes, Invisalign has changed the way our teenage patients view their orthodontic experience."

To mark this major milestone, Align Technology is reaffirming its previous commitment to help provide treatment to Operation Smile, which helps children around the world born with cleft lip and cleft palate.

Continued Hogan, “Through continuous innovation and new technology, we strive to provide Invisalign practices and their patients with the best treatment possible. We believe that every person should have access to the most advanced treatment options for a beautiful smile. To that end, we hope to inspire others to give more smiles to children in need with our continuing donation pledge to Operation Smile."


Starting 28th November, Align Technology would like to invite Invisalign patients and everyone around the world to help a child in need by participating in the “5 Million Smiles” social media campaign using the dedicated hashtag #5MillionSmiles. Each post of a person’s smile with the hashtag #5MillionSmiles published on Facebook, Instagram or Twitter, will be matched by Align Technology with a donation of $1 to Operation Smile for a total pledge up to $1 million [1].

Operation Smile is an international medical charity that has helped hundreds of thousands of children and young adults in developing countries who have been born with cleft lip, cleft palate or other facial deformities. It is one of the oldest and largest volunteer-based organisations dedicated to improving the health and lives of children worldwide through access to surgical care.

Since 1982, Operation Smile has developed expertise in mobilising volunteer medical teams in resource-poor environments while adhering to the highest standards of care and safety. Operation Smile helps provide access to safe, well-timed surgery by partnering with hospitals, governments and ministries of health, training local medical personnel, and donating much-needed supplies and equipment around the world.

Founded and based in Virginia, U.S., Operation Smile has extended its global reach to more than 60 countries through its network of surgeons, paediatricians, doctors, nurses, and student volunteers. For more information, visit

Note re #5MillionSmiles
[1] Align Technology donation pledge through to March 3, 2018. To date, Align has donated more than US$400 thousand to Operation Smile. Facebook shares must be made public in order to trigger the donation. Restrictions apply.
See the full terms and conditions at